Ultimate Gut Health Test
Uncover The Cause of Your Gut Symptoms.
Chronic constipation, diarrhoea, abdominal discomfort, and bloating are often placed under the umbrella of “IBS” or irritable bowel syndrome. Sometimes there are underlying causes of IBS that go undetected by conventional testing. Food allergies, maldigestion, parasites, yeast, and bacterial imbalances can all contribute to IBS.
The GI Effects Comprehensive Stool Profile provides data on inflammation and how well you digest and absorb the food you eat. Additionally, the profiles provide a detailed picture regarding the balance of yeast, parasites, and healthy and unhealthy bacteria that live in our large intestine. This bacterial population is called the microbiome. Many patients do not realise that in addition to gastro-intestinal complaints, systemic diseases can be linked to the GI tract. Improving the health of your gut may improve your overall health.
If you answer “yes” to any of these questions then digestive testing may be right for you.
- Do you have Irritable bowel syndrome?
- Do you frequently experience indigestion?
- Do you suffer from constipation?
- Do you often have unexplained diarrhoea?
- Do you experience gas and bloating?
- Do you ever have abdominal pain?
- Have you been diagnosed with Crohn’s disease?
- Do you have Ulcerative Colitis?
- Do you have food allergies or sensitivities?
- Do you suffer from fatigue?
- Do you consistently lack energy?
- Do you have Fibromyalgia?
- Do you have Rheumatoid arthritis?
- Do you have an auto immune condition?|
- Do you have poor skin or suffer from chronic skin conditions such as psoriosis or eczema?
- Have you used antibiotics on occasion?
About this test
The GI Effects Stool Profile offers a comprehensive look into digestive function. It provides information on the make-up of the gastrointestinal microbial abundance and balance. This bacterial population is called the microbiome. It includes good, imbalanced and potentially bad or harmful bacteria as well as looking for the presence of yeasts including candida plus it checks for parasites and worms. Additionally, the profile checks fat absorption, protein digestion, pancreatic function, intestinal inflammation, gut immunity and metabolic processes. The GI Effects can also help to provide new information to help differentiate between Irritable Bowel Syndrome (IBS) and Inflammatory Bowel Disease (IBD).
The GI Effects is at the forefront of testing, it covers a broad range of markers and uses the most up to date testing technology available.
What is being measured?
The GI Effects Profile checks 5 key areas of digestive health and wellness.
- Need for Digestive Support – this section checks your ability to digest and absorb macronutrients – protein, fats and carbohydrates.
- Need for Inflammation modulation – This section checks for inflammation in the gut which is associated with IBD – Inflammatory Bowel Disease such as Crohn’s or colitis. It also includes markers that are associated with the health of the gut wall and immune gut function.
- Need for Microbiome support – This section looks for levels of good, bad and imbalanced bacteria and yeasts.
- Need for Prebiotic Support – this section assesses the need for foods and supplements to support good bacteria such as fibre, prebiotics and probiotics. Good microbial balance influences many things such as immune function, bioavailability of nutrients and amongst other things levels of short chain fatty acids (SCFA’s) that are important for gut wall/gut mucosal integrity – linked to leaky gut and intestinal permeability.
- Need for Antimicrobial Support – this section reports on any findings that are related to infection such as any bad bacteria or potentially harmful parasites that may warrant antimicrobial support that may be pharmaceutical or herbal / plant based.
The individual markers measured are:
- Pancreatic Elastase-1 is a marker of exocrine pancreatic function.
- Products of Protein Breakdown are markers of undigested protein reaching the colon.
- Faecal Fat is a marker of fat breakdown and absorption
- Calprotectin is a marker of neutrophil-driven inflammation. Produced in abundance at sites of inflammation, this biomarker has been proven clinically useful in differentiating between Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS).
- Eosinophil Protein X is a marker of eosinophil-driven inflammation and allergic response.
- Faecal Secretory IgA is a marker of gut secretory immunity and barrier function.
- Faecal Occult Blood Test detects hidden blood; faecal immunochemical testing (FIT) has been recommended by the American College of Gastroenterology as the preferred noninvasive test for colorectal cancer screening/detection.
- Metabolic indicators, including short-chain fatty acids and beta-glucuronidase, demonstrate specific and vital metabolic functions performed by the microbiota.
- Commensal Bacteria demonstrate the composition and relative abundance of gut organisms.
- More than 95% of commensal gut organisms are anaerobic and are difficult to recover by traditional (aerobic) culture techniques.
- GI Effects assesses a set of 24 genera/species that map to 7 major phyla.
- Bacterial and mycology cultures- The process of culturing means that the lab checks for the presence of good, bad and imbalanced bacteria and yeasts by trying to grow them in a petri dish. If they manage to grow any bacteria or yeasts such as candida, they then treat them with pharmaceutical and natural antimicrobial agents to see which are sensitive – meaning which are reduced or killed off by the agent.
- Bacterial and mycology sensitivities- In the ever expanding world of microbial resistance, the sensitivity panel is a valuable tool to help inform which antimicrobial drugs or plant based antimicrobials may be most effective in addressing any imbalances and /or pathogens.
- Parasitology includes comprehensive testing for all parasites on every parasitology exam ordered.
- GI Effects provides microscopic faecal specimen examination for ova and parasites (O&P), the gold standard of diagnosis for many parasites. Highly skilled lab technicians check for eggs, parasites and yeast with a microscope.
- Polymerase chain reaction (PCR) targets detect common parasites including Blastocystis spp., Cryptosporidium parvum/hominis, Cyclospora cayetanensis, Dientamoeba fragilis, Entamoeba histolytica, and Giardia. The most up to date way of testing bacteria is to use a process called PCR – it means that the lab is looking at the DNA of bacteria which is more up to date than trying to culture bacteria – grow them in a petri dish. This is especially important as many bacteria are anaerobic – meaning they do not live in oxygen and therefore die soon after they have left the body. This makes culturing many bacteria impossible.
- Selection of a one-day or three-day sample collection is based on the clinician's clinical index of suspicion for parasitic infection. If there is no/low suspicion, a one-day sample will likely be adequate. For high suspicion, a three-day sample collection is optimal.
- Additional Biomarkers Available (contact for details):
- Clostridium difficile
- Escherichia coli
- Faecal Lactoferrin
- Helicobacter pylori
- Macro Exam for Worms
- Zonulin Family Peptide
- KOH Preparation for Yeast
Type of specimen required for the test
A Stool – 1 or 3 day collection with 6 vials or tubes to complete. The lab recommends samples are collected on 3 consecutive days but if this is not possible they should be collected over a week. If this is not possible please do get in touch to discuss options.
Returning your sample
You will need to send your sample back to the lab via a next day postal service – If you are in the UK, Royal mail offer a suitable next day service. If you are outside of the UK then please check with your postal service for options. The cost of the test does not cover the return postage.Please note that samples should only be posted on Monday – Thursday so that they do not arrive over the weekend when the lab is closed. A courier returns option is offered by the lab and details will be included in with your test kit. This is an optional service and the cost is not included in with the test fee. Details about payment, should you wish to take up this offer, are included with the courier details.
Age range this test is suitable for
Adults and children 2 years and above. The child needs to be potty trained and out of nappies. The sample must not be contaminated with urine or fibres from nappies. Please note the reference ranges for digestive and inflammatory markers are for adults.
Before taking this test
Refrain from taking digestive enzymes, antacids, and aspirin for two days prior to specimen collection, unless otherwise instructed by your healthcare provider. If taking antibiotics, antiparasitics, antifungals, probiotic supplements (acidophilus, etc.), or consuming food products containing beneficial flora (e.g. Activia®), it is recommended that you wait a minimum of 14 days after your last dose before beginning the test; 28 days may be preferred after antibiotics have been utilised (unless instructed otherwise by your physician). There may be times when your healthcare provider prefers that you stay on one of these agents (e.g. acidophilus) during testing in order to evaluate its effectiveness. Follow your healthcare provider’s recommendation. Never discontinue prescription medications without consulting your healthcare provider first. The test kit will come with full instructions.
How long does it take to get my results?
19 Working days
Your test results will be analysed by Dr Amina and you will receive a written explanation and treatment plan as well as your original test results.
How much does it cost?
The cost of the test is £499. This includes the cost of the test kit, return postage, lab analysis, test interpretation by Dr Amina Davison, a GMC registered doctor with further specialist training in Functional Medicine, written treatment plan including supplement regime.
How to order your test
- Create your account by completing the form below and complete your payment.
- In your personal dashboard please complete your address and date of birth so that you can receive your test pack and your samples can be correctly matched.
- You will be notified through the portal once your test kit has been dispatched and your health questionnaire will be added to your account for you to complete.
- Click on "Consent and Forms" in your dashboard to fill out your health questionnaire so that Dr Amina has all the information needed to create your treatment plan.
- Once you have completed and returned your samples, you will receive an email and text alert when your results are ready!
- You can also book a 30 or 60 minute consultation with Dr Amina if you would like to discuss your results in more detail and or get a deeper look into your health problems.
- If you have any queries along the way please email us at firstname.lastname@example.org.
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